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| Most Common Name: |
Khellin | | Also
Known As (other names): | |
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Khellin: A furanochromone found in the Khella
plant. Khellin is a furanocoumarin.
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Furanocoumarins: Furanocoumarins have sun- or
photosensitizing properties and are often used for the treatment of skin
conditions sometimes with controlled exposure to the sun.
Other effects of Furanocoumarins reportedly are: hypotensive activity,
antiasmatic and antispasmodic.
Furanocoumarins are potentially photo-carcinogenic and may promote a cancer that
is initiated by interference with the skins natural ability to protect
underlying cells against the carcinogenic effect of harmful ultra violet
radiation.
Furanocoumarins are Coumarins with a furan ring
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Coumarins: Coumarins are lactones of hydroxycinnamic
acids. Coumarins are lactones. There are many variations of coumarins: Furanocoumarins found in Angelica have a
spasmolitic effect but must be used with caution as they have a strong
phototoxic effect as has many of the Furanocoumarins (Warfarin a blood thinning
drug but also virulent rat poison, is a coumarin derivative). In general
coumarins have antifungal, hypotensive, anticoagulant and antimicrobial properties.
Many of the Coumarins are phototoxic and skin sensitising.
Lactones: A lactone is an Ester that's
functional group has become part of a ring structure with carbon atoms.
Lactones are widely present in the plant kingdom and many are expectorants and
febrifuges. |
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Khellin constituent is present in: |
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Medicinally Significant
volume |
Minor volume
Khellin is present in small quantities which may
not be enough to be a significant dosage for medicinal purposes
or is not the major constituent of this plant/herb |
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